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Welcome 1

Main Street Grille

Main Street Grille located on Walterboro, SC 29488. We have awesome recipes and the most talented chefs in town! We offer Fast, Relaxed, Healthy and stylish dining experience.

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Welcome 2
Come and See

Please call at (843) 782-4774 for a private tour or make a reservation.


Signature Dish

Explore texture, color and of course the ultimate tastes with our menu of the season. All the ingredients are fresh and carefully selected by our chefs. Enjoy an extraordinary dinning experience.

What Clients Say

Behind the Scenes

The Gallery

Every dish at Main Street Grille is a guaranteed must-have! From the short-rib ramen and chicken katsu, to all of the fresh sushi platters, it makes Osawa a go-to restaurant in Walterboro, SC for many locals. We hold ourselves to the highest standards, which gives us pride in being a consistently great and clean place for customers to order takeout from or dine-in at.

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